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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(SIT-rick acid/poh-TASS-ee-um, SO-dee-um SYE-trates)


This medication makes the urine less acidic. It is used in the treatment of certain kidney disorders and gout.

How To Use

This medication must be diluted in water before drinking to prevent stomach upset. Take the prescribed dose and dilute it in at least 1/2 glass of water. Stir to mix and drink, following with additional water. This is usually taken after meals and at bedtime. Do not lie down for 30 minutes after taking this medication. Take this medication as prescribed. Do not increase your dose or take this more often without your doctor's approval.

Side Effects

Notify your doctor if you develop: diarrhea, nausea, vomiting, stomach pain, fluid retention, convulsions, unusual weakness, mental confusion, tingling or numbness of the hands or feet. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: kidney problems, heart disease, liver disease, Addison's disease, high blood pressure, a sodium-(salt)restricted diet (this medication contains sodium), allergies (especially drug allergies). This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take, including: lithium, chlorpropamide, methotrexate, aspirin, water pills, certain heart medications (e.g., quinidine, digoxin), certain blood pressure medications (e.g., ACE inhibitors such as lisinopril; angiotensin blockers such as losartan), methenamine, tetracyclines (including doxycycline and minocycline), potassium supplements, azole antifungals (e.g., ketoconazole). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, weakness, confusion, irregular heartbeat, or fainting.


While taking this medication, it may be necessary for you to test the pH (acidity) of your urine using special paper. The pH will help determine the proper dose.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


The liquid may be stored at room temperature or in the refrigerator, which will help improve the flavor.