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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling (inflammation), in particular menstrual pain (dysmenorrhea). This drug works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling.



This medication may also be used to treat arthritis (rheumatoid-type) and to reduce fever.

How To Use

Take this medication by mouth usually once or twice daily either with or without food or take as directed by your doctor. Take this medication with a full glass (8 oz or 240 ml) of water unless your doctor directs you otherwise. Do not lie down for 30 minutes after taking this medication. The dosage is based on your medical condition and response to therapy.

Side Effects

Stomach upset, nausea, diarrhea, or headache may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: swelling, unusual tiredness and weakness, weight gain. Tell your doctor immediately if any of these unlikely but serious side effects occur: change in amount of urine, dizziness, blurred vision, yellowing eyes or skin, dark urine. If you notice any of these highly unlikely but very serious side effects, stop taking valdecoxib and consult your doctor or pharmacist immediately: coffee-ground vomit, black stools, persistent stomach pain. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


This medication is not recommended for use if you have the following medical conditions: kidney disease, severe liver disease, allergies to sulfas, aspirin, or NSAID (e.g., ibuprofen, celecoxib). Tell your doctor your medical history, especially of: liver problems, asthma, nasal polyps, swelling problems (fluid retention), stomach problems (e.g., bleeding, ulcers), blood disorders (e.g., anemia), heart disease, high blood pressure, tobacco or alcohol use, dehydration, poorly controlled diabetes, any allergies. This medication may cause stomach bleeding. Daily use of alcohol and this medication may increase your risk for stomach bleeding. This medication should be used only when clearly needed during pregnancy but should not be used during the third trimester. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: aspirin or aspirin-like drugs (e.g., NSAIDs such as ibuprofen, naproxen), azole antifungals (e.g., fluconazole, itraconazole, ketoconazole), "blood thinners" (e.g., warfarin), ACE inhibitors (e.g., captopril, lisinopril), "water pills" (diuretics such as furosemide, hydrochlorothiazide), dextromethorphan, lithium. Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) which are similar to this drug. Aspirin, as prescribed by your doctor for reasons such as heart attack or stroke prevention (usually these dosages are 81-325 mg per day), should be continued. Consult your doctor or pharmacist for more details. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: drowsiness, vomiting, or stomach pain.


Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor your progress. This medication has been prescribed for your current condition only. Do not use it for other pain-related conditions unless told to do so by your doctor. A different medication may be necessary in those cases.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture.