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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(METH-ih-leen blue)


This medication is used as a diagnostic agent because of its blue staining properties. This is also used in the treatment of cyanide poisoning and methemoglobinemia (a blood disorder).

How To Use

This medication is given by intravenous (IV) injection over several minutes by a health care professional.

Side Effects

Nausea, stomach upset, diarrhea, vomiting or bladder irritation may occur. If any of these effects continue or become bothersome, notify your doctor. This medication causes the urine, stools and possibly skin to turn green-blue in color. Do not be alarmed. Expect this effect. The discoloration will disappear when the medication is stopped. Notify your doctor if you notice: high fever, severe nausea and vomiting, abdominal pain, headache, chest pain, dizziness, profuse sweating. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: kidney disease, blood blood disorders (especially G6PD deficiency), allergies. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


This medication is given by intravenous injection only.

Missed Dose

This is usually given as a one-time dose.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat, light and moisture. Do not store in the bathroom.