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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(kan-a-MYE-sin SUL-fate)



Kanamycin is an antibiotic used for the short-term treatment of certain bacterial infections.

How To Use

Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have questions regarding the use of this medication, consult your pharmacist. Give this medication by vein (IV) or directly into a muscle (IM) as directed by your doctor. Depending on your medical condition, you may receive this medication by another route (e.g., topically or inhaled). The dosage and length of treatment is based on your medical condition and response to therapy. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, give the drug at evenly spaced intervals. Continue to use this medication until the fully-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. To minimize serious side effects, do not use more than 1.5 grams per day of this medication or use this medication for longer than seven to 10 days, unless directed by your doctor. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Headache, nausea, vomiting, diarrhea, or pain at the injection site may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: changes in hearing, feeling of fullness or ringing in the ears, dizziness, eye/vision problems, loss of appetite, tingling or numbness of the skin/hands/feet, seizures, weakness, muscle cramps, tremors, persistent fever, change in the amount of urine, bloody or pink-colored urine. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. Use of this medication for prolonged or repeated periods may result in a secondary infection (e.g., oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or any other new symptoms. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: kidney problems, severe burns, cystic fibrosis, muscle problems (e.g., myasthenia gravis, Parkinson's disease, botulism), dehydration, ear/hearing problems or problems with balance (vestibular problems), any allergies (especially to sulfites or to aminoglycosides such as gentamicin or streptomycin). Caution is advised when using this drug in young infants because they may be more sensitive to the effects of this drug (e.g., may cause kidney problems). Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of this drug (e.g., may cause kidney problems). This medication is not recommended for use during pregnancy. Consult your doctor before using this drug. This drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: penicillin antibiotics (e.g., penicillin, ampicillin), cephalosporin antibiotics (e.g., cefazolin, cefotetan), acyclovir, vancomycin, amphotericin B, bacitracin, colistin, cisplatin, cyclosporine, drugs for water loss (diuretics such as furosemide, ethacrynic acid, or mannitol), anesthesia or muscle relaxing agents (e.g., succinylcholine, tubocurarine), certain blood products (citrate- anticoagulated blood), anti-nausea drugs (e.g., dimenhydrinate), aspirin and/or NSAIDs (e.g., ibuprofen, naproxen). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: ringing in the ears, change in amount of urine.


Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor for side effects and response to treatment.

Missed Dose

If you miss a dose or your dose is interrupted, contact your doctor or pharmacist immediately to establish a new dosing schedule.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture. After dilution in correct IV fluids (consult your pharmacist for details), the drug is stable at room temperature for 24 hours. Discard any unused liquid.