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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Ertapenem is an antibiotic used to treat a variety of severe bacterial infections (e.g., pneumonia, abdominal infections, skin infections, urinary tract/kidney infections).

How To Use

Follow all directions for proper mixing and dilution with the correct IV fluids. If you have questions regarding the use of this medication, consult your pharmacist. Inject this medication into a muscle (IM) or give by vein (IV) over 30 minutes in a saline solution usually once daily, or as directed by your doctor. The dosage and length of treatment is based on your medical condition and response to therapy. Do not mix this medication in dextrose-containing solutions (e.g., D5W). If this medication is being given into a muscle (IM), follow all directions for mixing with an anesthetic solution (e.g., lidocaine 1%). Doing so may help relieve some of the discomfort from the IM injection. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform your doctor if your condition does not improve in 3 days. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Diarrhea, nausea, vomiting, headache, constipation, and injection site reactions (e.g., pain, redness, swelling) may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, swelling, fever, dizziness, blurred vision, trouble sleeping, trouble breathing, mental/mood changes, irritation/itching of the vagina. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: seizures, unusually fast heartbeat, chest pain, unusual fatigue. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, dizziness, swelling, trouble breathing. Use of this medication for prolonged or repeated periods may result in a secondary infection (e.g., oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: kidney problems, brain or seizure disorders, any allergies. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. Tell your doctor if you are pregnant before using this medication. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: other antibiotics, probenecid, phenothiazines (e.g., chlorpromazine, thioridazine), tricyclic antidepressants (e.g., amitriptyline, nortriptyline), theophylline, caffeine, sympathomimetics (e.g., amphetamine, methylphenidate), isoniazid, salicylates, tacrine, donepezil, morphine. This product can affect the results of certain lab tests (e.g., liver function tests-LFT's). Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe nausea/vomiting/dizziness.


This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases. Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor your progress.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store the unmixed vials/powder at room temperature (77 degrees F or 25 degrees C). Once mixed, the medication should be given (if IM) or further diluted in a saline solution immediately after mixing. After mixing and subsequent dilution with IV fluids, this product is stable at room temperature for 6 hours, or refrigerated (between 36 and 46 degrees F or 2 and 8 degrees C) for 24 hours. Do not freeze.