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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.



COMMON BRAND NAME(S): Bravelle, Fertinex, Follistim, Gonal-F


This medication is used in combination with hCG hormone to assist in ovulation and fertility if clomiphene treatment fails. The medication is also used with in-vitro fertilization methods.

How To Use

This drug is injected under the skin after preparation of the solution, exactly as instructed. The dosage is adjusted to each individual's response. Usually daily intercourse is recommended, beginning on the day before the hCG hormone is given, until ovulation occurs (e.g., rise in basal body temperature). Follow MD instructions. The liquid should be visually checked before injection for particles or discoloration and discarded if contaminated. Follow instructions for proper disposal of syringes and supplies. Do not reuse needles or syringes.

Side Effects

Breast tenderness, mild diarrhea, nausea or vomiting might occur. If these persist or worsen, notify your doctor promptly. Report promptly: bloating, pelvic or belly pain, redness/pain/ swelling at the injection site. Unlikely but report promptly: breathing problems, leg swelling or pain, one-sided muscle weakness, vision changes. Very unlikely but report promptly: severe stomach/abdominal pain, decreased urine amount, rapid weight gain, fever, skin rash or hives. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history, especially of: any allergies, cancer or tumors, abnormal uterine bleeding, thyroid or adrenal gland problems, other infertility problems, ovarian cysts or enlargements. Multiple births might occur as a result of this therapy. This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. It is not known whether this drug is excreted into human milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you use. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


Do not share this medication with others. Laboratory tests and ultrasound procedures will usually be necessary.

Missed Dose

If you miss a dose of either urofollitropin or hCG hormone, consult your doctor promptly for advice.


Store the powder refrigerated or at room temperature between 37 and 77 degrees F (3-25 degrees C) away from light and moisture. Use immediately after mixing the saline solution with the powder. Discard unused material.